When the valves are damaged, the blood moves in both directions (up and down) which causes abnormal pressures (venous hypertension) and symptoms such as leg pain, swelling, itching, cramping, heaviness, fatigue, discomfort and restless legs. The abnormal pressures can also cause varicose veins, spider veins, leg ulcers, skin discoloration, and thickening. Symptoms can worsen over time and if left untreated.